Roll-over Study for Patients Who Have Completed a Prior Novartis-sponsored Sabatolimab (MBG453) Study and Are Judged by the Investigator to Benefit From Continued Treatment With Sabatolimab.

Inclusion Criteria:

1. Participant is currently enrolled in a Novartis-sponsored study with sabatolimab, is
being treated with sabatolimab, and has fulfilled all requirements in the parent
study.

2. Participant is currently benefiting from the treatment with sabatolimab as
determined by guidelines of the parent protocol and investigator's judgment.

3. Participant has demonstrated compliance, as assessed by the investigator, with the
parent study protocol requirements.

4. Willingness and ability to comply with scheduled visits, treatment plan and any
other study procedures.

5. Written informed consent obtained prior to enrolling in the roll-over study.

Exclusion Criteria:

1. Participants in cohorts or treatment groups not receiving sabatolimab in the parent
protocol.

2. Participant has been permanently discontinued from sabatolimab treatment in the
parent study due to unacceptable toxicity, non-compliance to study procedures,
withdrawal of consent or any other reason.

3. Participant currently has unresolved toxicities for which sabatolimab dosing has
been interrupted in the parent study (participants meeting all other eligibility
criteria may be enrolled once toxicities have resolved to allow sabatolimab dosing
to resume).

4. Pregnant or nursing (lactating) women. Where pregnancy is defined as the state of a
female after conception confirmed by a positive serum hCG laboratory test and until
the termination of gestation.

5. Participant not willing to comply with the contraception requirements outlined in
the exclusion criteria of the parent protocol.

6. Local access to commercially available sabatolimab for parent protocol indications.

Other protocol-defined Inclusion/Exclusion may apply.