Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location

A Study of Efficacy and Safety of Ianalumab Versus Placebo in Addition to Eltrombopag in Primary Immune Thrombocytopenia Patients Who Failed Steroids

Primary Immune Thrombocytopenia Phase3 United States
China
France
Czechia
Hungary
Argentina
Australia
Germany
Belgium
Austria
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Phase 3b Study to Assess the Efficacy, Safety, and Tolerability of Remibrutinib in Comparison to Placebo, With Omalizumab as Active Control, in Adult CSU Patients, Followed by an Open-label 52-week Optional Extension.

Chronic Spontaneous Urticaria Phase3 Brazil
Germany
Argentina
France
Czechia
Canada
Australia
Bulgaria
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Study Assessing the Efficacy, Safety and PK of Alpelisib (BYL719) in Pediatric and Adult Patients With PIK3CA-related Overgrowth Spectrum

PIK3CA-related Overgrowth Spectrum (PROS) Phase2 United States
Switzerland
France
Germany
Spain
United Kingdom
Canada
Netherlands
Hong Kong
Italy
China
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Three-arm Study to Assess Efficacy and Safety of Ianalumab (VAY736) in Patients With Active Sjogren's Syndrome

Sjogren Syndrome Phase3

The Belgian REAL (BE.REAL) Registry

Atherosclerotic Cardiovascular Disease Belgium

Phase 3 Study to Evaluate Two Regimens of Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 1)

Systemic Lupus Erythematosus Phase3 United States
China
Brazil
Bulgaria
Canada
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Long-term Safety, Tolerability and Effectiveness Study of Ofatumumab in Patients With Relapsing MS

Relapsing Multiple Sclerosis Phase3 United States

A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis

Aortic Stenosis Phase2 United States
Switzerland
Israel
Czechia
United Kingdom
Canada
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Roll-over Study to Allow Continued Access to Ribociclib

Metastatic Breast Cancer Phase4 United States
South Africa
Turkey
Brazil
Poland
Hong Kong
Italy
Costa Rica
Argentina
Taiwan
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Effectiveness of Brolucizumab in Pre-treated Patients With nAMD in the Real-world Setting

Neovascular Age-related Macular Degeneration United Arab Emirates