Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location

Study of Efficacy and Safety of JDQ443 Single-agent as First-line Treatment for Patients With Locally Advanced or Metastatic KRAS G12C- Mutated Non-small Cell Lung Cancer With a PD-L1 Expression < 1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutation.

Locally Advanced or Metastatic KRAS G12C-mutated NSCLC With a PD-L1 Expression <1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutation Phase 2 United States
Turkey
Malaysia
Greece
Thailand
Spain
Italy
China
Brazil
Germany
Bulgaria
Netherlands
France
Argentina
Austria
India
Portugal
Hungary
Belgium
Singapore
United Kingdom
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Study of Efficacy, Safety and Tolerability of Remibrutinib in Adult Participants With an Allergy to Peanuts

Allergy, Peanut Phase 2 United States
Spain

Study of Efficacy and Safety of Ribociclib (LEE011) in Combination With Topotecan and Temozolomide (TOTEM) in Pediatric Patients With Relapsed or Refractory Neuroblastoma and Other Solid Tumors

Neuroblastoma Phase 1, Phase 2 United States
Spain
Germany
Italy
Australia
Singapore
France
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A Phase I/II Study of DYP688 in Patients With Metastatic Uveal Melanoma and Other GNAQ/11 Mutant Melanomas

Metastatic Uveal Melanoma Phase 1, Phase 2 United States
Germany
Netherlands
Spain
Australia
France
Switzerland
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Study Evaluating Effectiveness and Adherence of Inclisiran Plus Standard of Care (SoC) Lipid-lowering Therapy Compared to SoC in ASCVD

Primary Hypercholesterolemia, Mixed Dyslipidemia United Arab Emirates
Switzerland
United Kingdom
Austria
Israel
Saudi Arabia
Malaysia
China
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Study of PIT565 in Relapsed and/or Refractory B-cell Malignancies

B-cell Non-Hodgkin Lymphoma (B-NHL), B-cell Acute Lymphoblastic Leukemia (B-ALL) Phase 1 United States
Spain
Italy
Belgium
Japan
France
Singapore
Israel
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Asciminib Monotherapy, With Dose Escalation, for 2nd and 1st Line Chronic Myelogenous Leukemia

Chronic Myelogenous Leukemia - Chronic Phase Phase 2 United States

Efficacy and Safety of Secukinumab in Patients With New Onset of Giant Cell Arteritis Who Are in Clinical Remission

Giant Cell Arteritis Phase 3 Germany

A Non-interventional Implementation Study to Evaluate Treatment With Inclisiran (Leqvio®) and Other Lipid Lowering Treatments in a Real-world Setting

Hypercholesterolemia Germany

Coronary Computed Tomography Study to Assess the Effect of Inclisiran in Addition to Maximally Tolerated Statin Therapy on Atherosclerotic Plaque Progression in Participants With a Diagnosis of Non-obstructive Coronary Artery Disease Without Previous Cardiovascular Events

Coronary Artery Disease Phase 3 United States
Spain
Belgium
Australia
India
China
United Kingdom
Hungary
Argentina
Korea, Republic of
Brazil
Ireland
Switzerland
Japan
Italy
Canada
France
Chile
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