Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location

Study to Determine the Dose and Safety of Asciminib in Pediatric Patients With Chronic Myeloid Leukemia

Myeloid Leukemia, Philadelphia Positive Phase1, Phase2 United States
Greece
Thailand
China
France
Hungary
Turkey
Germany
Italy
Russian Federation
Japan
Korea, Republic of
Netherlands
Poland
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The Gilenya Pregnancy Registry

Multiple Sclerosis Denmark
Portugal
Netherlands
Greece
Argentina
Lebanon
Germany
Colombia
Australia
Belgium
France
Romania
Hungary
United States
Italy
Ireland
Austria
Saudi Arabia
Israel
Poland
Mexico
Russian Federation
Cyprus
Czechia
Brazil
Canada
Finland
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Study of Efficacy and Safety of Ribociclib (LEE011) in Combination With Topotecan and Temozolomide (TOTEM) in Pediatric Patients With Relapsed or Refractory Neuroblastoma and Other Solid Tumors

Neuroblastoma Phase1, Phase2 United States
Spain
Germany
Italy
Australia
Singapore
France
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Asciminib Prospective Non Interventional Study as 3rd Line Therapy or More to Treat Adult Patients With CML- CP in Real World Setting in France

Chronic Myeloid Leukemia France

A Study to Investigate the Safety, Tolerability and Preliminary Efficacy of NGI226 Microparticles in Patients With Achilles Tendinopathy

Achilles Tendinopathy Phase2 United States
Germany
France
United Kingdom
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[177Lu]Lu-NeoB in Combination With Ribociclib and Fulvestrant in Participants With ER+, HER2- and GRPR+ Advanced Breast Cancer

Breast Cancer Phase1 Spain
France
Germany
Poland
Portugal
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A Phase 1 Study to Evaluate the Pharmacokinetics of JDQ443 in Participants With Hepatic Impairment Compared to Matched Healthy Control Participants.

Small Cell Lung Carcinoma Phase1 United States

Study of HRO761 Alone or in Combination in Cancer Patients With Specific DNA Alterations Called Microsatellite Instability or Mismatch Repair Deficiency.

MSIhi or dMMR Advanced Unresectable or Metastatic Solid Tumors, Including Colorectal Cancers Phase1 United States
Spain
France
Belgium
Germany
Japan
Italy
Norway
Korea, Republic of
Singapore
Sweden
Taiwan
Israel
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An Extension Study of Long-term Efficacy, Safety and Tolerability of Remibrutinib in Chronic Spontaneous Urticaria Patients Who Completed Preceding Studies With Remibrutinib

Chronic Spontaneous Urticaria Phase3 United States
Argentina

A Study to Investigate Efficacy, Safety, and Tolerability of Remibrutinib Compared With Placebo in Adults With CINDU Inadequately Controlled by H1-antihistamines

Chronic Inducible Urticaria Phase3 United States
Argentina
Australia
China
Canada
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